ANTIBODIES THAT BIND TO SARS-COV-2

To provide novel antibodies that allow for prevention and/or treatment of COVID-19.SOLUTION: Disclosed is an antibody or fragment thereof that binds to S1 subunit of SARS-CoV-2, which comprises a heavy chain CDR1 of a specific amino acid sequence, a heavy chain CDR2 of a specific amino acid sequence...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SHIGA HAZUKI, MATSUKURA SUSUMU, WATANABE SHINYA, HOSHI HIROTAKA, SATO SHIGEKO, IMAI JUNICHI
Format: Patent
Sprache:eng ; jpn
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Beschreibung
Zusammenfassung:To provide novel antibodies that allow for prevention and/or treatment of COVID-19.SOLUTION: Disclosed is an antibody or fragment thereof that binds to S1 subunit of SARS-CoV-2, which comprises a heavy chain CDR1 of a specific amino acid sequence, a heavy chain CDR2 of a specific amino acid sequence, a heavy chain CDR3 of a specific amino acid sequence, a light chain CDR1 of a specific amino acid sequence, a light chain CDR2 of a specific amino acid sequence and a light chain CDR3 of a specific amino acid sequence.SELECTED DRAWING: None 【課題】本発明は、COVID-19に対する感染予防および/または治療を可能とする新規抗体の提供を課題とする。【解決手段】特定のアミノ酸配列からなる重鎖CDR1、特定のアミノ酸配列からなる重鎖CDR2、特定のアミノ酸配列からなる重鎖CDR3、特定のアミノ酸配列からなる軽鎖CDR1、特定のアミノ酸配列からなる軽鎖CDR2、および、特定のアミノ酸配列からなる軽鎖CDR3を有する抗体であって、SARS-CoV-2のS1サブユニットに結合する、抗体またはその抗体フラグメント。【選択図】なし