ANTIBODIES TO FELINE MCDONOUGH SARCOMA (FMS)-LIKE TYROSINE KINASE 3 RECEPTOR LIGAND (FLT3L) AND USES THEREOF FOR TREATING AUTOIMMUNE AND INFLAMMATORY DISEASES

To provide anti-FLT3L antibodies and methods of using the antibodies to treat autoimmune and other inflammatory diseases.SOLUTION: The invention provides an antibody or antigen-binding fragment thereof that binds to FLT3L, where the antibody or antigen-binding fragment thereof comprises a set of Com...

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Hauptverfasser:	ANNA HANSEN, CATHERINE RACHEL ETTINGER, XIAO XIAODONG, PETER PAVLIK, CHEN YAN
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	To provide anti-FLT3L antibodies and methods of using the antibodies to treat autoimmune and other inflammatory diseases.SOLUTION: The invention provides an antibody or antigen-binding fragment thereof that binds to FLT3L, where the antibody or antigen-binding fragment thereof comprises a set of Complementarity-Determining Regions (CDRs): HCDR1, HCDR2, HCDR3, LCDR1, LCDR2 and LCDR3, where the HCDR1, HCDR2, HCDR3, LCDR1, LCDR2 and LCDR3 comprise respective specific amino acid sequences.SELECTED DRAWING: None 【課題】抗ＦＬＴ３Ｌ抗体、並びに自己免疫疾患及び他の炎症性疾患を治療するために、該抗体を使用する方法を提供する。【解決手段】ＦＬＴ３Ｌに特異的に結合する抗体又はその抗原結合断片であって、相補性決定領域（ＣＤＲ）の組：ＨＣＤＲ１、ＨＣＤＲ２、ＨＣＤＲ３、ＬＣＤＲ１、ＬＣＤＲ２及びＬＣＤＲ３を含み、前記ＨＣＤＲ１、ＨＣＤＲ２、ＨＣＤＲ３、ＬＣＤＲ１、ＬＣＤＲ２及びＬＣＤＲ３は、各々特定のアミノ酸配列を含む、抗体又はその抗原結合断片を提供する。【選択図】なし