SCREENING SYSTEM AND SCREENING METHOD AS WELL AS METHOD FOR PRODUCING ANIMAL CELLS AND PROTEINS USING THE SAME

To provide a screening system that suppresses damage to animal cells and can obtain animal cells with high production capacity for target proteins.SOLUTION: A screening system 1 comprises: a container 10 for containing a suspension containing a plurality of animal cells separated from each other; a...

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Hauptverfasser:	IKEDA RYOSUKE, ISO YOSHIYUKI, OKA DAIKI, KANEKO YO
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	To provide a screening system that suppresses damage to animal cells and can obtain animal cells with high production capacity for target proteins.SOLUTION: A screening system 1 comprises: a container 10 for containing a suspension containing a plurality of animal cells separated from each other; a gas supply unit 20 that supplies gas into the container 10; and a fluid force separation device 30 that comprises a curved channel having a rectangular cross section and separates relatively large animal cells among the animal cells contained in the suspension supplied by pressurizing gas from the container 10 by a vortex flow generated by flowing through a curved channel.SELECTED DRAWING: Figure 1 【課題】動物細胞へのダメージを抑制し、標的タンパク質の産生能力が高い動物細胞を取得することが可能なスクリーニングシステムを提供する。【解決手段】スクリーニングシステム１は、互いに分離された複数の動物細胞を含む懸濁液を収容する容器１０と、容器１０内にガスを供給するガス供給部２０と、矩形断面を有する湾曲流路を含み、容器１０からガスの加圧によって供給された懸濁液に含まれる動物細胞のうち相対的に大きい動物細胞を、湾曲流路を流れることによって生じる渦流れによって分離する流体力分離装置３０とを備える。【選択図】図１