CELL SEPARATION SUBSTRATE AND CELL SEPARATION METHOD

To provide a cell separation substrate that can adsorb a specific cell selectively, allows the cell to be easily desorbed from the cell separation substrate, and further can give a high-purity cell, and a cell separation method using the substrate.SOLUTION: A cell separation substrate has a substrat...

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Hauptverfasser:	IMAMURA RYUTARO, MARUYAMA ATSUSHI, OTAKE TOMOYUKI, SHIMADA NAOHIKO
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC MACROMOLECULAR COMPOUNDS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS THEIR PREPARATION OR CHEMICAL WORKING-UP VINEGAR WINE
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Beschreibung
Zusammenfassung:	To provide a cell separation substrate that can adsorb a specific cell selectively, allows the cell to be easily desorbed from the cell separation substrate, and further can give a high-purity cell, and a cell separation method using the substrate.SOLUTION: A cell separation substrate has a substrate whose surface is fixed with a copolymer having at least an ureido group-containing repetitive sequence, which is a repeat of a specific ureido group-containing structure, and a charge-containing repetitive sequence, with its upper limit critical solution temperature (UCST) ranging from 4°C to 50°C.SELECTED DRAWING: None 【課題】特定の細胞を選択的に吸着でき、細胞を細胞分離用基材から脱離させやすく、さらには純度の高い細胞が得られる細胞分離用基材、および該基材を用いた細胞分離方法を提供する。【解決手段】基材表面に少なくとも特定のウレイド基含有構造の繰り返しであるウレイド基含有繰り返し配列と電荷含有繰り返し配列とを有し、上限臨界溶液温度（ＵＣＳＴ）が４～５０℃の範囲である共重合体が固定化された細胞分離用基材を提供する。【選択図】なし