METHOD FOR PRODUCING TERTIARY ALCOHOL HAVING 2,3-DIALKYL AROMATIC GROUP

To provide a method for inexpensively producing a tertiary alcohol having a 2,3-dialkyl aromatic group.SOLUTION: In a method for producing a tertiary alcohol represented by general formula (3), a Grignard reagent is synthesized by making a chlorine-containing aromatic compound and magnesium react with each other in the presence of 0.1-2.0 equivalent of lithium chloride with respect to the chlorine-containing aromatic compound. After making the Grignard reagent and a ketone compound react with each other at 15-40°C, the synthesis is conducted by hydrolysis treatment using an aqueous solution including an acid with pKa of 2 or more (each of R1, R2, R3 and R4 indicates an alkyl group).SELECTED DRAWING: None 【課題】２，３－ジアルキル芳香族を有する第３級アルコールを、安価に製造する方法の提供。【解決手段】塩素含有芳香族化合物とマグネシウムを、塩素含有芳香族化合物に対し０．１～２．０当量の塩化リチウムの存在下で反応させグリニャール試薬を合成し、グリニャール試薬とケトン化合物を１５～４０℃で反応させた後、ｐＫａが２以上の酸を含む水溶液を用いて加水分解処理して合成する、一般式（３）で示される第３級アルコールの製造方法。TIFF2022071252000011.tif33142（Ｒ１、Ｒ２、Ｒ３、Ｒ４はアルキル基を示す）【選択図】なし