BODY FLUID ANTIBODY BIOMARKER FOR DETECTING ARTERY PLAQUE LESION AND DETECTING BRAIN AND CARDIOVASCULAR DISORDER, DIABETES, CHRONIC KIDNEY DISEASE, OR SOLID CANCER

To provide a comprehensive biomarker for diabetes, heart disease, cerebrovascular disorder, cancer, kidney disease, etc., which can suppress artery plaque lesion and the occurrence and progress thereof through a health care such as an early diagnosis.SOLUTION: It has been found that the above proble...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: NAKAMURA RIKA, HIWASA SHIGEKI, TOMIYOSHI GO, KURODA HIDEYUKI
Format: Patent
Sprache:eng ; jpn
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:To provide a comprehensive biomarker for diabetes, heart disease, cerebrovascular disorder, cancer, kidney disease, etc., which can suppress artery plaque lesion and the occurrence and progress thereof through a health care such as an early diagnosis.SOLUTION: It has been found that the above problem can be solved by measuring an antibody level in a body fluid sample, separated from a living organism, against KIAA0513 protein or a portion thereof and acquiring data on an increase in the antibody level as presence data of artery plaque lesion or as clear or presence data of brain and cardiovascular disorder, diabetes, chronic kidney disease, or solid cancer.SELECTED DRAWING: None 【課題】 動脈病変、さらには、早期診断等の健康管理により発生や進行を抑えることができる、糖尿病、心疾患、脳血管障害、がん、腎臓病等に関する、包括的なバイオマーカーの提供。【解決手段】 KIAA0513蛋白質又はその一部、に対する生体から分離された体液サンプル中の抗体レベルを測定し、当該抗体レベルの上昇データを、動脈病変の存在データ、或いは、脳心臓血管障害、糖尿病、慢性腎臓病、又は固形癌の、潜在若しくは顕在データとして取得することにより、上記の課題を解決することができることを見出した。【選択図】 なし