ALBUMIN COMPOSITION, AND METHOD FOR PRODUCING AND USING THE SAME

To provide an albumin composition having a defined fatty acid profile, and a method for using the composition.SOLUTION: An albumin composition described in the specification is suitable for being used particularly in a cell culture method and a method for stabilizing protein. The albumin composition...

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Bibliographische Detailangaben
Hauptverfasser:	HSIEH CHEN-YU, HUANG PO-YI, HSU MENG-TSUNG, JEFFY CHERN, CHEN PEIIN, LIANG YU-FENG
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	To provide an albumin composition having a defined fatty acid profile, and a method for using the composition.SOLUTION: An albumin composition described in the specification is suitable for being used particularly in a cell culture method and a method for stabilizing protein. The albumin composition described in the specification can improve the viability of a cell (e.g. mammalian cell) and/or promote proliferation of the cell in the case where the cell is cultured in a culture medium containing the albumin composition. The albumin composition described in the specification can improve the stability of a biological preparation in the case where the biological preparation is in the presence of the albumin composition. Further provided in the specification is a method for blending the albumin composition having a defined fatty acid profile as described in the specification.SELECTED DRAWING: Figure 1 【課題】定義された脂肪酸プロファイルを有するアルブミン組成物及びそれを使用する方法を提供すること。【解決手段】本明細書に記載のアルブミン組成物は、特に、細胞培養方法、タンパク質安定化方法において使用するために好適である。本明細書に記載のアルブミン組成物は、細胞(例えば、哺乳動物細胞)がアルブミン組成物を含有する培地中で培養された場合に、細胞の生存能力を向上させ且つ/又は増殖を促進しうる。本明細書に記載のアルブミン組成物は、生物学的製剤がアルブミン組成物の存在下にある場合、生物学的製剤の安定性を向上させうる。本明細書に記載されるような定義された脂肪酸プロファイルを有するアルブミン組成物を配合する方法が本明細書において更に提供される。【選択図】図１