GEL MATERIAL FOR TREATING TENDON OR LIGAMENT

To provide a gel material that suppresses intrusion of a scar structure in treatment of a tendon or a ligament, promotes healing due to inter-tendon cells, and makes an intrinsic function of the tendon efficiently recover, and a treatment method.SOLUTION: A gel material containing a polymer gel for...

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Hauptverfasser: TANAKA SAKAE, IWANAGA YASUHIDE, NARITA SHINICHI, SAKAI TAKAMASA, MASUI KOSUKE, SAITO TAKUMA
Format: Patent
Sprache:eng ; jpn
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Zusammenfassung:To provide a gel material that suppresses intrusion of a scar structure in treatment of a tendon or a ligament, promotes healing due to inter-tendon cells, and makes an intrinsic function of the tendon efficiently recover, and a treatment method.SOLUTION: A gel material containing a polymer gel for suppressing expression of type III collagen in treatment of injury or rupture of tendons or ligaments, in which the polymer gel is a hydro gel having a structure in which a three-dimensional network structure is formed by crosslinking a hydrophilic polymer, has a polymer content in a range of 1 to 5 wt.%, and an elastic modulus in a range of 100 to 10000 Pa.SELECTED DRAWING: None 【課題】腱又は靭帯の治療において瘢痕組織の進入を抑制し、腱内細胞による治癒を促進し、腱本来の機能を効率的に回復させる、ゲル材料、及び治療方法の提供。【解決手段】腱又は靭帯の損傷又は断裂の治療においてIII型コラーゲンの発現を抑制するための、高分子ゲルを含むゲル材料であって、前記高分子ゲルが、親水性ポリマーが架橋することにより3次元網目構造を形成した構造を有するハイドロゲルであって、1~5重量%の範囲の高分子含有量、及び100~10000Paの範囲の弾性率を有することを特徴とする、該ゲル材料。【選択図】なし