AUTOINDUCER-2 INHIBITOR

To provide an AI-2 inhibitor having the activity of inhibiting autoinducer-2.SOLUTION: When copper gluconate and zinc gluconate are used in a concentration range in which they do not exhibit antibacterial activity (i.e, a concentration range in which they do not inhibit the proliferation and/or grow...

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Bibliographische Detailangaben
Hauptverfasser:	HAMADA MASAKO, GOMI MITSUHIRO
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
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Beschreibung
Zusammenfassung:	To provide an AI-2 inhibitor having the activity of inhibiting autoinducer-2.SOLUTION: When copper gluconate and zinc gluconate are used in a concentration range in which they do not exhibit antibacterial activity (i.e, a concentration range in which they do not inhibit the proliferation and/or growth of bacteria), they show excellent activity of inhibiting AI-2 and can be used as active ingredients of an AI-2 inhibitor.SELECTED DRAWING: None 【課題】本発明の目的は、オートインデューサー−２に対して阻害活性を有するＡＩ−２阻害剤を提供することである。【解決手段】グルコン酸銅及びグルコン酸亜鉛は、抗菌活性を発揮しない濃度範囲（即ち、細菌の増殖及び／又は生育を抑制しない濃度範囲）で使用すると、ＡＩ−２に対して優れた阻害活性を示し、ＡＩ−２阻害剤の有効成分として利用できる。【選択図】なし