METHOD FOR PRODUCING O-SUBSTITUTED HYDROXYLAMINE DERIVATIVE

METHOD FOR PRODUCING O-SUBSTITUTED HYDROXYLAMINE DERIVATIVE

To provide a method for efficiently producing an O-substituted hydroxylamine derivative useful as an active ingredient of an aldehyde scavenger.SOLUTION: A method for producing an O-substituted hydroxylamine derivative (1) includes hydrolyzing 2-[(1,3-dioxoisoindoline-2-yl)oxy]carboxylate ester with...

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Hauptverfasser: NAGAI YASUYUKI, TSUBOI YUKI, MASUDA TAKAHIRO, SUNAKAWA AYA, TACHIMOTO TOMOKO, ICHIJO HIROKI, KOBAYASHI OSAMU
Format: Patent
Sprache:eng ; jpn
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:To provide a method for efficiently producing an O-substituted hydroxylamine derivative useful as an active ingredient of an aldehyde scavenger.SOLUTION: A method for producing an O-substituted hydroxylamine derivative (1) includes hydrolyzing 2-[(1,3-dioxoisoindoline-2-yl)oxy]carboxylate ester with sulfonic acid and treating it with a group 2 element. (R1 is H or a C1-4 alkyl group).SELECTED DRAWING: None 【課題】アルデヒド捕捉剤の有効成分として有用なＯ−置換ヒドロキシルアミン誘導体の効率的な製造方法の提供。【解決手段】２−［（１，３−ジオキソイソインドリン−２−イル）オキシ］カルボン酸エステルをスルホン酸で加水分解し、第２族元素で処理する、Ｏ−置換ヒドロキシルアミン誘導体（１）の製造方法。（Ｒ１はＨ、又はＣ１〜４のアルキル基。）【選択図】なし