CATHETER
To provide a catheter capable of reliably releasing a medicament at a target portion while protecting a medicament layer during inserting a baloon, and a method to manufacture the catheter.SOLUTION: A catheter 10 comprises a long-sized shaft 11 and a balloon 12 placed on the tip side of the shaft 11...
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Zusammenfassung: | To provide a catheter capable of reliably releasing a medicament at a target portion while protecting a medicament layer during inserting a baloon, and a method to manufacture the catheter.SOLUTION: A catheter 10 comprises a long-sized shaft 11 and a balloon 12 placed on the tip side of the shaft 11 and expandable radially. The balloon 12 has on its surface a base layer 30 containing a temperature responsive polymer having the lowest critical solution temperature lower than a body temperature. The base layer 30 has a hydrophobic medicament layer 31 containing a medicament, on its surface opposite from a surface facing the balloon 12.SELECTED DRAWING: Figure 3
【課題】バルーンの挿入時には薬剤層を保護しつつ目的部位では確実に薬剤を放出できるカテーテル及びその製造方法を提供する。【解決手段】長尺なシャフト部11と、シャフト部11の先端側に配置され径方向に拡張可能なバルーン12と、を有し、バルーン12は、下限臨界溶液温度が体温より低い温度応答性高分子を含むベース層30を表面に有し、ベース層30は、薬剤を含む疎水性の薬剤層31をバルーン12に面する表面と反対側の表面に有するカテーテル10である。【選択図】図3 |
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