COLONY STIMULATING FACTOR-1 RECEPTOR (CSF-1R) INHIBITOR

To provide compounds useful as colony stimulating factor-1 receptor (csf-1r) inhibitors.SOLUTION: This invention relates to a compound of formula (II). (n is 1; p is 1; X1 is C, N or CR7; X2-X7 are each N, NR7, or CR7; X8 and X9 are each N or C; T1, T2, and T3 are each N or CR10; R7 and R10 are each...

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Bibliographische Detailangaben
Hauptverfasser:	MA LIANG, METZ MARKUS, PATRICK SHUM, PAUL ERDMAN, VINOD PATEL, TIEU-BINH LE, MARK CZEKAJ, MICHAEL KOTHE, JOHN L KANE JR, LIU JINYU, WEI LINLI, CLAUDE BARBERIS, BARRET GIESE, ANDREW SCHOLTE
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	To provide compounds useful as colony stimulating factor-1 receptor (csf-1r) inhibitors.SOLUTION: This invention relates to a compound of formula (II). (n is 1; p is 1; X1 is C, N or CR7; X2-X7 are each N, NR7, or CR7; X8 and X9 are each N or C; T1, T2, and T3 are each N or CR10; R7 and R10 are each H, C1 to C10 alkyl or the like; R1, R2, R5 and R6 are each H, C1 to C10 alkyl or the like; and Z1 is H, halo, C1 to C10 alkyl or the like).SELECTED DRAWING: None 【課題】コロニー刺激因子−１受容体阻害剤として有用な化合物を提供する。【解決手段】式（ＩＩ）の化合物。（ｎ：１。ｐ：１。Ｘ１：Ｃ、Ｎ、ＣＲ７。Ｘ２〜Ｘ７：Ｎ、ＮＲ７、ＣＲ７。Ｘ８、Ｘ９：Ｎ、Ｃ。Ｔ１、Ｔ２、Ｔ３：Ｎ、ＣＲ１０。Ｒ７、Ｒ１０：Ｈ、Ｃ１〜Ｃ１０アルキルなど。Ｒ１、Ｒ２、Ｒ５、Ｒ６：Ｈ、Ｃ１〜Ｃ１０アルキルなど。Ｚ１：Ｈ、ハロ、Ｃ１〜Ｃ１０アルキルなど。）【選択図】なし