BREAST CANCER EVALUATION METHOD, AND URINE TEST KIT FOR BREAST CANCER EVALUATION

To provide a method for simply and noninvasively evaluating the breast cancer without subjecting a breast to an examination object, and also to provide a urine test kit for evaluating a breast cancer.SOLUTION: A breast cancer evaluation method of the present invention includes a step (A1) of measuri...

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Hauptverfasser: YOKOMORI HIROAKI, KIKUCHI KIYOSHI, OKAZAKI ISAO, UEMATSU TAKAYUKI, ANDO WATARU, KOUGO YUTAKA, ODORI KATSUYA
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creator YOKOMORI HIROAKI
KIKUCHI KIYOSHI
OKAZAKI ISAO
UEMATSU TAKAYUKI
ANDO WATARU
KOUGO YUTAKA
ODORI KATSUYA
description To provide a method for simply and noninvasively evaluating the breast cancer without subjecting a breast to an examination object, and also to provide a urine test kit for evaluating a breast cancer.SOLUTION: A breast cancer evaluation method of the present invention includes a step (A1) of measuring a matrix metalloprotease-1 (MMP-1) contained in a urinary exosome of a subject. The breast cancer evaluation method of the present invention includes a step (B1) of measuring a micro RNA 21 (miR21) contained in the urinary exosome of the subject. A urine test kit for breast cancer evaluation of the present invention includes an exosome preparation reagent and a matrix metalloprotease 1 (MMP-1) measurement reagent.SELECTED DRAWING: None 【課題】本発明は、乳房を検査の対象とせず、簡便かつ非侵襲的に乳がんを評価する方法、および乳がん評価用の尿検査キットを提供することを課題とする。【解決手段】本発明の乳がん評価方法は、対象の尿中エクソソームに含まれる、マトリックスメタロプロテアーゼ−1(MMP−1)を測定する工程(A1)を含む。本発明の乳がん評価方法は、対象の尿中エクソソームに含まれる、マイクロRNA21(miR21)を測定する工程(B1)を含む。本発明の乳がん評価用の尿検査キットは、エクソソーム調製試薬と、マトリックスメタロプロテアーゼ−1(MMP−1)測定試薬とを含む。【選択図】なし
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The breast cancer evaluation method of the present invention includes a step (B1) of measuring a micro RNA 21 (miR21) contained in the urinary exosome of the subject. A urine test kit for breast cancer evaluation of the present invention includes an exosome preparation reagent and a matrix metalloprotease 1 (MMP-1) measurement reagent.SELECTED DRAWING: None 【課題】本発明は、乳房を検査の対象とせず、簡便かつ非侵襲的に乳がんを評価する方法、および乳がん評価用の尿検査キットを提供することを課題とする。【解決手段】本発明の乳がん評価方法は、対象の尿中エクソソームに含まれる、マトリックスメタロプロテアーゼ−1(MMP−1)を測定する工程(A1)を含む。本発明の乳がん評価方法は、対象の尿中エクソソームに含まれる、マイクロRNA21(miR21)を測定する工程(B1)を含む。本発明の乳がん評価用の尿検査キットは、エクソソーム調製試薬と、マトリックスメタロプロテアーゼ−1(MMP−1)測定試薬とを含む。【選択図】なし</description><language>eng ; jpn</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; PHYSICS ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20210408&amp;DB=EPODOC&amp;CC=JP&amp;NR=2021056103A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76517</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20210408&amp;DB=EPODOC&amp;CC=JP&amp;NR=2021056103A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>YOKOMORI HIROAKI</creatorcontrib><creatorcontrib>KIKUCHI KIYOSHI</creatorcontrib><creatorcontrib>OKAZAKI ISAO</creatorcontrib><creatorcontrib>UEMATSU TAKAYUKI</creatorcontrib><creatorcontrib>ANDO WATARU</creatorcontrib><creatorcontrib>KOUGO YUTAKA</creatorcontrib><creatorcontrib>ODORI KATSUYA</creatorcontrib><title>BREAST CANCER EVALUATION METHOD, AND URINE TEST KIT FOR BREAST CANCER EVALUATION</title><description>To provide a method for simply and noninvasively evaluating the breast cancer without subjecting a breast to an examination object, and also to provide a urine test kit for evaluating a breast cancer.SOLUTION: A breast cancer evaluation method of the present invention includes a step (A1) of measuring a matrix metalloprotease-1 (MMP-1) contained in a urinary exosome of a subject. 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The breast cancer evaluation method of the present invention includes a step (B1) of measuring a micro RNA 21 (miR21) contained in the urinary exosome of the subject. A urine test kit for breast cancer evaluation of the present invention includes an exosome preparation reagent and a matrix metalloprotease 1 (MMP-1) measurement reagent.SELECTED DRAWING: None 【課題】本発明は、乳房を検査の対象とせず、簡便かつ非侵襲的に乳がんを評価する方法、および乳がん評価用の尿検査キットを提供することを課題とする。【解決手段】本発明の乳がん評価方法は、対象の尿中エクソソームに含まれる、マトリックスメタロプロテアーゼ−1(MMP−1)を測定する工程(A1)を含む。本発明の乳がん評価方法は、対象の尿中エクソソームに含まれる、マイクロRNA21(miR21)を測定する工程(B1)を含む。本発明の乳がん評価用の尿検査キットは、エクソソーム調製試薬と、マトリックスメタロプロテアーゼ−1(MMP−1)測定試薬とを含む。【選択図】なし</abstract><oa>free_for_read</oa></addata></record>
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PHYSICS
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
TESTING
VINEGAR
WINE
title BREAST CANCER EVALUATION METHOD, AND URINE TEST KIT FOR BREAST CANCER EVALUATION
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