BREAST CANCER EVALUATION METHOD, AND URINE TEST KIT FOR BREAST CANCER EVALUATION

To provide a method for simply and noninvasively evaluating the breast cancer without subjecting a breast to an examination object, and also to provide a urine test kit for evaluating a breast cancer.SOLUTION: A breast cancer evaluation method of the present invention includes a step (A1) of measuri...

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Hauptverfasser:	YOKOMORI HIROAKI, KIKUCHI KIYOSHI, OKAZAKI ISAO, UEMATSU TAKAYUKI, ANDO WATARU, KOUGO YUTAKA, ODORI KATSUYA
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	To provide a method for simply and noninvasively evaluating the breast cancer without subjecting a breast to an examination object, and also to provide a urine test kit for evaluating a breast cancer.SOLUTION: A breast cancer evaluation method of the present invention includes a step (A1) of measuring a matrix metalloprotease-1 (MMP-1) contained in a urinary exosome of a subject. The breast cancer evaluation method of the present invention includes a step (B1) of measuring a micro RNA 21 (miR21) contained in the urinary exosome of the subject. A urine test kit for breast cancer evaluation of the present invention includes an exosome preparation reagent and a matrix metalloprotease 1 (MMP-1) measurement reagent.SELECTED DRAWING: None 【課題】本発明は、乳房を検査の対象とせず、簡便かつ非侵襲的に乳がんを評価する方法、および乳がん評価用の尿検査キットを提供することを課題とする。【解決手段】本発明の乳がん評価方法は、対象の尿中エクソソームに含まれる、マトリックスメタロプロテアーゼ−１（ＭＭＰ−１）を測定する工程（Ａ１）を含む。本発明の乳がん評価方法は、対象の尿中エクソソームに含まれる、マイクロＲＮＡ２１（ｍｉＲ２１）を測定する工程（Ｂ１）を含む。本発明の乳がん評価用の尿検査キットは、エクソソーム調製試薬と、マトリックスメタロプロテアーゼ−１（ＭＭＰ−１）測定試薬とを含む。【選択図】なし