HETEROCYCLIC COMPOUND AND USE THEREOF

To provide a heterocyclic compound that can have an antagonistic action on an NMDA receptor containing an NR2B subunit and that is expected to be useful as a prophylactic or therapeutic agent for depression, bipolar disorder, migraine, pain, peripheral symptoms of dementia and the like.SOLUTION: A c...

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Bibliographische Detailangaben
Hauptverfasser:	YONEMORI JINICHI, TAKAKURA NOBUYUKI, KAMIYA HIROTAKA, TANAKA TOSHIO, OGURO YUYA, ITO MITSUHIRO, IKEDA SHUHEI, WAKABAYASHI KENJI, HIRAYAMA KOJI, MATSUMOTO SHIGEMITSU, KAMATA MAKOTO, KAMEI TAKU, FUJIMOTO TAKUYA, TOKUNAGA NORIHITO, SAKANO HIROSHI
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	To provide a heterocyclic compound that can have an antagonistic action on an NMDA receptor containing an NR2B subunit and that is expected to be useful as a prophylactic or therapeutic agent for depression, bipolar disorder, migraine, pain, peripheral symptoms of dementia and the like.SOLUTION: A compound represented by the structure of formula (I), such as 6-(difluoromethoxy)-5-fluoro-N-[(4-methoxypyridine-3-yl)methyl]pyridine-3-carboxamide, or a salt thereof.SELECTED DRAWING: None 【課題】ＮＲ２Ｂサブユニットを含むＮＭＤＡ受容体の拮抗作用を有し得、うつ病、双極性障害、片頭痛、疼痛、認知症周辺症状等の予防または治療剤として有用であることが期待される複素環化合物を提供すること。【解決手段】式（Ｉ）：の構造で表される、6-(ジフルオロメトキシ)-5-フルオロ-N-[(4-メトキシピリジン-3-イル)メチル]ピリジン-3-カルボキサミド、等の化合物またはその塩。【選択図】なし