PLACENTA-DERIVED ADHERENT CELL EXOSOMES AND USES THEREOF

To provide compositions of placenta-derived adherent cell exosomes and methods of making and using the same.SOLUTION: A composition comprises exosomes derived from human placenta-derived adherent cells, where the exosomes are CD9+, CD10+, CD13+, CD29+, CD44+, CD49b+, CD49c+, CD55+, CD59+, CD63+, CD7...

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Bibliographische Detailangaben
Hauptverfasser:	IVANA DJURETIC, ERIC LAW, ANDREW MORSCHAUSER, KATHY E KARASIEWICZ-MENDEZ, ALLAN REDUTA, VLADIMIR JANKOVIC, JENNIFER PAREDES, ALEKSANDAR FRANCKI
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	To provide compositions of placenta-derived adherent cell exosomes and methods of making and using the same.SOLUTION: A composition comprises exosomes derived from human placenta-derived adherent cells, where the exosomes are CD9+, CD10+, CD13+, CD29+, CD44+, CD49b+, CD49c+, CD55+, CD59+, CD63+, CD73+, CD81+, CD82+, CD90+, CD98+, CD105+, CD141+, CD142+, CD151+, CD164+, CD295+, or CD200+.SELECTED DRAWING: Figure 1 【課題】胎盤由来の接着細胞エクソソームの組成物、ならびにこれを作製及び使用する方法を提供する。【解決手段】ヒト胎盤由来の接着細胞由来のエクソソームを含む組成物であって、前記エクソソームは、ＣＤ９＋、ＣＤ１０＋、ＣＤ１３＋、ＣＤ２９＋、ＣＤ４４＋、ＣＤ４９ｂ＋、ＣＤ４９ｃ＋、ＣＤ５５＋、ＣＤ５９＋、ＣＤ６３＋、ＣＤ７３＋、ＣＤ８１＋、ＣＤ８２＋、ＣＤ９０＋、ＣＤ９８＋、ＣＤ１０５＋、ＣＤ１４１＋、ＣＤ１４２＋、ＣＤ１５１＋、ＣＤ１６４＋、ＣＤ２９５＋、またはＣＤ２００＋である。【選択図】図１