SURFACE MODIFICATION MAGNETIC PARTICLES AND METHOD FOR MANUFACTURING THE SAME

To provide surface modification magnetic particles that have a high biology-related substance combining ability, a high nonspecific adsorption suppression capability, and a high stability to a change of pH.SOLUTION: Surface modification magnetic particles can be provided with a high biology-related...

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Bibliographische Detailangaben
Hauptverfasser:	INOUE HIROSHI, KONDO SATOSHI, TSUNEFUJI SUKIAKI
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	To provide surface modification magnetic particles that have a high biology-related substance combining ability, a high nonspecific adsorption suppression capability, and a high stability to a change of pH.SOLUTION: Surface modification magnetic particles can be provided with a high biology-related substance combining ability, a high nonspecific adsorption suppression capability, and a high stability to a change of pH by including three layers of an acid polysaccharide coat layer, a polyamine cross-linked layer, and a polycarboxylic acid coat layer in the surface of the magnetic particles.SELECTED DRAWING: None 【課題】高い生体関連物質結合能と非特異吸着抑制能、更に、ｐＨの変動に対する安定性が高い表面修飾磁性粒子を提供する。【解決手段】磁性粒子表面に、酸性多糖類コート層、ポリアミン架橋層、ポリカルボン酸コート層の順に三層を有することで、高い生体関連物質結合能と非特異吸着抑制能、更に、ｐＨの変動に対する安定性が高い表面修飾磁性粒子が得られる。【選択図】なし