REPROGRAMMING T-CELL AND HEMATOPOIETIC CELL

To provide a reprogramming T-cell and a hematopoietic cell, a method related to production of an artificial pluripotent stem cell (iPS cell), and a composition.SOLUTION: A method for producing an artificial pluripotent stem cell from a T-cell or a CD34+ hematopoietic progenitor cell includes: (a) a process of acquiring a cell population including a T-cell or a CD34+ hematopoietic progenitor cell, in which the CD34+ hematopoietic progenitor cell is derived from a subject, and the cell of the subject is not mobilized by an externally added granulocyte colony stimulating factor (G-CSF); and (b) a process of producing iPS cells from the T-cell or the CD34+ hematopoietic progenitor cell of the cell population to provide an iPS cell population.SELECTED DRAWING: None 【課題】リプログラミングＴ細胞及び造血細胞、人工多能性幹細胞（ｉＰＳ細胞）の産生に関連した方法及び組成物の提供。【解決手段】Ｔ細胞又はＣＤ３４＋造血始原細胞から人工多能性幹細胞を作製する方法であって、（ａ）Ｔ細胞又はＣＤ３４＋造血始原細胞を含む細胞集団を入手する工程であって、ＣＤ３４＋造血始原細胞が、被験体に由来し、被験体の細胞が、外的に加えられる顆粒球コロニー刺激因子（Ｇ−ＣＳＦ）で動員されていない、工程と、（ｂ）細胞集団のＴ細胞又はＣＤ３４＋造血始原細胞からｉＰＳ細胞を産生させて、ｉＰＳ細胞集団を提供する工程と、を含む、方法。【選択図】なし