4 - IMIDAZOPYRIDAZIN- 1 -YL-BENZAMIDES AND 4 - IMIDAZOTRIAZIN- 1 - YL - BENZAMIDES AS BTK- INHIBITORS

To provide compounds useful for the treatment of Bruton's Tyrosine Kinase (Btk) mediated disorders.SOLUTION: There is provided a compound having 4-imidazopyridazin-1-yl-benzamide structure including compounds represented by the following formula, or a pharmaceutical composition including these...

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Hauptverfasser:	JOHANNES BERNARDUS MARIA REWINKEL, DE ADRIANUS PETRUS ANTONIUS MAN, HANS C A RAAIJMAKERS, CHRISTIAAN GERARDUS JOHANNES MARIA JANS, JACOBUS C H M WIJKMANS, TJEERD A BARF, JAN-GERARD STERRENBURG, ARTHUR A OUBRIE
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	To provide compounds useful for the treatment of Bruton's Tyrosine Kinase (Btk) mediated disorders.SOLUTION: There is provided a compound having 4-imidazopyridazin-1-yl-benzamide structure including compounds represented by the following formula, or a pharmaceutical composition including these compounds.SELECTED DRAWING: None 【課題】ブルトン型チロシンキナーゼ（Ｂｔｋ）媒介障害の処置に有効な化合物の提供。【解決手段】下記式で代表される化合物を含む、４−イミダゾピラジンー１−イル−ベンズアミド構造を有する化合物、又はこれらの化合物を含む医薬組成物。【選択図】なし