MYOCARDIAL REGENERATION PROMOTING COMPOUNDS, PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION, AND THEIR USE

To provide a novel compound that can improve regeneration and repair of myocardial cells, and thereby provide a non-invasive, therapeutic method for myocardial infarction.SOLUTION: The present invention discloses a novel 3-aryl-2-propen-1-one series derivative and a synthesis processes thereof. Besi...

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Bibliographische Detailangaben
Hauptverfasser: HUANG BI-CAN, TSAI HUI-PING, XU LI-XIE, WU YING-YING, RIN YI-WEN, CHEN MEI-HWAI, LEE LAIN-TZE, HUANG SHU-FEN
Format: Patent
Sprache:eng ; jpn
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Zusammenfassung:To provide a novel compound that can improve regeneration and repair of myocardial cells, and thereby provide a non-invasive, therapeutic method for myocardial infarction.SOLUTION: The present invention discloses a novel 3-aryl-2-propen-1-one series derivative and a synthesis processes thereof. Besides, the present invention also discloses use of a pharmaceutical composition and a series derivative thereof for promoting myocardial regeneration.SELECTED DRAWING: Figure 2 【課題】心筋細胞の再生及び修復を改善する新規化合物、及びそれにより、非侵襲性の心筋梗塞治療方法の提供を目的とする。【解決手段】本願発明は、新規な3−アリール−2−プロペン−1−オン系誘導体及びその合成工程を含む。また、本願発明は、心筋再生を促進させるための医薬組成物及びその派生物系の使用を開示する。【選択図】図2