DISACCHARIDE SYNTHETIC LIPID COMPOUNDS AND USES THEREOF

To provide compounds useful as immunostimulants for inducing and stimulating an immune response, and useful as adjuvants in immunogenic compositions such as vaccines.SOLUTION: Synthetic disaccharide lipid compounds, illustrated by e.g. the following formula, chemically synthesized and provided in es...

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Bibliographische Detailangaben
Hauptverfasser:	MARIA PILAR LOPEZ-DEBER, DAVID T HICKMAN, STEPHEN W BURGESS, LI SHENGRONG, WALTER A SHAW
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	To provide compounds useful as immunostimulants for inducing and stimulating an immune response, and useful as adjuvants in immunogenic compositions such as vaccines.SOLUTION: Synthetic disaccharide lipid compounds, illustrated by e.g. the following formula, chemically synthesized and provided in essentially pure form. The compounds are preferably at least 99% pure.SELECTED DRAWING: Figure 6 【課題】免疫応答を誘導し、刺激するための免疫刺激剤として有用であり、免疫原性組成物、例えばワクチン中のアジュバントとして有用である化合物の提供。【解決手段】例えば下式で例示される、化学的に合成され本質的に純粋な合成二糖脂質化合物。該化合物は、少なくとも９９％純粋であることが好ましい。【選択図】図６