PHARMACEUTICAL CONTAINER AND LIQUID COMPOSITION

To provide a pharmaceutical container comprising a stopper properly sealing the container and having proper break loose force and glide force.SOLUTION: There is provided a pharmaceutical container 1 for drug delivery comprising: a barrel 2; and a stopper 3. The stopper 3 is arranged in the barrel 2...

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1. Verfasser: HORSCH ELMAR
Format: Patent
Sprache:eng ; jpn
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Zusammenfassung:To provide a pharmaceutical container comprising a stopper properly sealing the container and having proper break loose force and glide force.SOLUTION: There is provided a pharmaceutical container 1 for drug delivery comprising: a barrel 2; and a stopper 3. The stopper 3 is arranged in the barrel 2 in a slidable manner and comprises one or a plurality of annular protrusions 12 which contact an inner surface 5 of the barrel 2 when moving in a distal direction. The annular protrusions 12 have rising edges and falling edges in a proximal-distal direction. A ratio X/A of an angle X of the annular protrusion closest to the stopper 3 and an angle A of the annular protrusion farthest is at least 1.05, a ratio of break loose force (BLF) to glide force (GF) satisfies BLF/GF≤2, and a total glide force variation TGFV=GFmax-GFmin which is measured when the stopper 3 is moved from a start end position to its end position satisfies TGFV