BIOMOLECULE ANALYZER AND BIOMOLECULE ANALYSIS METHOD

To suppress the occurrence of background noise and measure target molecules with a high S/N ratio.SOLUTION: A biomolecule analyzer of the present disclosure comprises a thin film having nanopores, a pair of liquid tanks for accommodating an electrolyte solution and arranged so as to sandwich the thin film, a pair of electrodes respectively arranged in the pair of liquid tanks, and a measurement unit connected to the pair of electrodes. The electrolyte solution is such that biomolecules with which modification molecules are modified are dissolved in it, and pH is greater than 8.0, and when the pH of the electrolyte solution is greater than 8.0, the passage of modification molecules as single units through the nanopores is blocked.SELECTED DRAWING: Figure 1 【課題】バックグラウンドノイズの発生を抑制し、高ＳＮ比で対象分子を計測する。【解決手段】本開示の生体分子分析装置は、ナノポアを有する薄膜と、前記薄膜を挟むよう配置され、電解質溶液を収容する一対の液槽と、前記一対の液槽のそれぞれに配置される一対の電極と、前記一対の電極に接続される測定部と、を備える。前記電解質溶液は、修飾分子が修飾された生体分子が溶解され、ｐＨが８．０より大きく、前記修飾分子は、前記電解質溶液のｐＨが８．０より大きい場合、単体では前記ナノポアの通過が阻止されることを特徴とする。【選択図】図１