USE OF S1P RECEPTOR MODULATOR

To provide use of an S1P receptor modulator in the treatment or prevention of a disease or condition dependent on brain-derived neurotrophic factor (BDNF) expression.SOLUTION: The present invention provides a pharmaceutical composition for preventing, inhibiting or treating Rett syndrome, the compos...

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Bibliographische Detailangaben
Hauptverfasser:	MATSUMOTO TOMOYA, GRAEME BILBE, ANIS KHUSRO MIR, KUHN RAINER R, YVES-ALAIN BARDE, ANNA SVENJA SCHUBART, RUBEN DEOGRACIAS
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	To provide use of an S1P receptor modulator in the treatment or prevention of a disease or condition dependent on brain-derived neurotrophic factor (BDNF) expression.SOLUTION: The present invention provides a pharmaceutical composition for preventing, inhibiting or treating Rett syndrome, the composition comprising 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol in free form or in a pharmaceutically acceptable salt form.SELECTED DRAWING: Figure 1 【課題】脳由来神経栄養因子（ＢＤＮＦ）の発現に依存する疾患あるいは症状の処置または予防におけるＳ１Ｐ受容体調節因子の使用。【解決手段】レット症候群を予防、抑制または治療するための医薬組成物であって、遊離形態または薬学的に許容される塩の形態の２−アミノ−２−［２−（４−オクチルフェニル）エチル］プロパン−１，３−ジオールを含有する組成物。【選択図】図１