EFFICIENT CLUSTERING OF IMMUNOLOGICAL ENTITIES
To provide a method of grouping immunological entities which can be clinically applied with high precision in the field of immune-related diseases.SOLUTION: Without predefining functions, generality of so-called antigen specificity, which is dealt with as a separate "function" (e.g., prese...
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Zusammenfassung: | To provide a method of grouping immunological entities which can be clinically applied with high precision in the field of immune-related diseases.SOLUTION: Without predefining functions, generality of so-called antigen specificity, which is dealt with as a separate "function" (e.g., presence or absence of specificity to an antigen A), is normally assumed for each immunological entity conjugate (antigen and epitope), and similarity thereof is evaluated to group immunological entities.SELECTED DRAWING: Figure 1A
【課題】免疫関連の疾患について、精確度が高い、臨床応用が可能な免疫実体を分類する手法を提供する。【解決手段】機能をあらかじめ規定しないで、通常、免疫実体結合物(抗原やエピトープ)を個々に別の「機能(=例えば、抗原Aに対する特異性を持つかどうか)」として取り扱われる抗原特異性というものに一般性があると仮定し、それの類似度を評価することで、免疫実体を分類する。【選択図】図1A |
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