METHOD FOR PRODUCING SOLID PREPARATION

To provide a method for producing a solid preparation containing ibuprofen and other medicinal components, solving a poor appearance such as pestle attachment.SOLUTION: The present invention provides a method for producing a solid preparation containing two or more medicinal components including ibu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser:	NISHI AKIKO
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	To provide a method for producing a solid preparation containing ibuprofen and other medicinal components, solving a poor appearance such as pestle attachment.SOLUTION: The present invention provides a method for producing a solid preparation containing two or more medicinal components including ibuprofen, having the steps of (i) agitating and granulating ibuprofen as a separate group from other medicinal components, and (ii) blending a fumarate or an ester thereof or a salt thereof.SELECTED DRAWING: None 【課題】杵付着などの外観不良が改善された、イブプロフェンと他の薬効成分を含有する固形製剤の製造方法を提供すること。【解決手段】イブプロフェンを含む２種以上の薬効成分を含有する固形製剤の製造方法であって、（i）イブプロフェンを他の薬効成分とは別群で攪拌造粒する工程と、（ii）フマル酸若しくはそのエステル又はそれらの塩を配合する工程を具備することを特徴とする、固形製剤の製造方法。【選択図】なし