THERAPEUTIC AGENTS FOR TREATMENT OF DISEASES ASSOCIATED WITH UNDESIRED CELL PROLIFERATION

To provide methods for treatment of diseases associated with undesired cell proliferation, and more specifically, cancer and tumor stem cells.SOLUTION: A pharmaceutical composition for treatment of diseases associated with undesired cell proliferation comprises an inhibitor of expression and/or acti...

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Bibliographische Detailangaben
Hauptverfasser:	JOAN SEOANE SUAREZ, SILVIA PENUELAS PRIETO, BASELGA TORRES JOSE
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	To provide methods for treatment of diseases associated with undesired cell proliferation, and more specifically, cancer and tumor stem cells.SOLUTION: A pharmaceutical composition for treatment of diseases associated with undesired cell proliferation comprises an inhibitor of expression and/or activity of a leukemia inhibitory factor (LIF), where the diseases associated with undesired cell proliferation are cancers selected from breast, heart, lung, small intestine, colon, spleen, bladder, head, neck, ovarian, brain, pancreatic, skin, bone, bone marrow, blood, thymus, uterine, testicular and liver tumors.SELECTED DRAWING: Figure 1 【課題】望ましくない細胞増殖と関連する疾患、より具体的には、癌および腫瘍幹細胞の治療方法の提供。【解決手段】白血病阻害因子（ＬＩＦ）の発現および／または活性の阻害剤を含む、望ましくない細胞増殖と関連する疾患の治療のための医薬組成物であって、望ましくない細胞増殖と関連する疾患が癌であり、癌が、乳房、心臓、肺、小腸、結腸、脾臓、膀胱、頭部、頸部、卵巣、脳、膵臓、皮膚、骨、骨髄、血液、胸腺、子宮、精巣および肝臓の腫瘍から選択される、医薬組成物。【選択図】図１