ARTIFICIAL NUCLEOSIDE, ARTIFICIAL NUCLEOTIDE, AND ARTIFICIAL OLIGONUCLEOTIDE

PROBLEM TO BE SOLVED: To provide an artificial nucleoside and artificial nucleotide that can form an artificial oligonucleotide having excellent nuclease resistance.SOLUTION: There is provided an artificial nucleoside or artificial nucleotide which is a compound and salt thereof represented by follo...

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1. Verfasser:	IRIYAMA YUSUKE
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS SUGARS VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide an artificial nucleoside and artificial nucleotide that can form an artificial oligonucleotide having excellent nuclease resistance.SOLUTION: There is provided an artificial nucleoside or artificial nucleotide which is a compound and salt thereof represented by following formula (I). (In the formula, Bx is a pyrimidine base or a purine base, R, R, R, and Rare hydrogen atoms, C1-6 alkyl groups, etc., Zand Zare hydrogen atoms, hydroxyl group protective groups, phosphorus-containing groups, etc.)SELECTED DRAWING: None 【課題】ヌクレアーゼ耐性に優れる人工ヌオリゴクレオチドを構成可能な人工ヌクレオシド又は人工ヌクレオチドを提供する。【解決手段】下記式（Ｉ）で表される化合物及びその塩である人工ヌクレオシド又は人工ヌクレオチドである。（Ｂｘはピリミジン塩基又はプリン塩基であり、Ｒ１、Ｒ２、Ｒ３及びＲ４は水素原子、Ｃ１−６アルキル基等であり、Ｚ１及びＺ２は水素原子、ヒドロキシ基保護基、リン含有基等である。）【選択図】なし