METHOD OR KIT FOR DIAGNOSING NONALCOHOLIC FATTY LIVER DISEASE

PROBLEM TO BE SOLVED: To provide a novel method of diagnosing nonalcoholic fatty liver disease (NAFLD), and to provide a diagnostic kit for nonalcoholic fatty liver disease.SOLUTION: Presence/absence or severity of NAFLD can be effectively and noninvasively diagnosed by measuring a level of at least...

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Bibliographische Detailangaben
Hauptverfasser:	TANAKA YOSHIAKI, ONO YASUSHI, KESSOKU TAKAOMI, NAKAJIMA ATSUSHI, SHIMAKAWA MAKI
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a novel method of diagnosing nonalcoholic fatty liver disease (NAFLD), and to provide a diagnostic kit for nonalcoholic fatty liver disease.SOLUTION: Presence/absence or severity of NAFLD can be effectively and noninvasively diagnosed by measuring a level of at least one substance selected from a group consisting of pyridoxamine, carboxymethyl lysine, 5-amino valeric acid, linoleoyl ethanolamide, oleoylethanolamide, and indole-3-carbaldehyde in feces, and/or occupancy of faecalibacterium in feces.SELECTED DRAWING: None 【課題】本発明の目的は、新規な非アルコール性脂肪性肝疾患（ＮＡＦＬＤ）の診断方法を提供することである。さらに本発明の目的は、非アルコール性脂肪性肝疾患の診断用キットを提供することである。【解決手段】糞便中のピリドキサミン、カルボキシメチルリジン、５−アミノ吉草酸、リノレオイルエタノールアミド、オレオイルエタノールアミド及びインドール−３−カルボアルデヒドからなる群より選択される少なくとも一種の量及び／又はフィーカリバクテリウム属の菌の占有率を測定することにより、ＮＡＦＬＤの有無、又はＮＡＦＬＤの重症度を効率的かつ非侵襲的に診断することができる。【選択図】なし