PHARMACEUTICAL COMPOSITION FOR RELAPSE, WORSENING OR METASTASIS OF LIVER CANCER

PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for inhibiting relapse, worsening or metastasis of liver cancer.SOLUTION: The present invention provides a pharmaceutical composition for inhibiting relapse, worsening or metastasis of liver cancer, comprising a therapeutically effective...

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Bibliographische Detailangaben
Hauptverfasser:	ZHANG SHIZHONG, LAI KUAN-LANG
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for inhibiting relapse, worsening or metastasis of liver cancer.SOLUTION: The present invention provides a pharmaceutical composition for inhibiting relapse, worsening or metastasis of liver cancer, comprising a therapeutically effective amount of a specific sulfated oligosaccharide. The sulfated oligosaccharide is an oligosaccharide molecule with 2-5 mannose units linked via 1→3 and/or 1→2 glycosidic bonds, having a phosphate group or a sulfate group, for example, obtained by hydrolyzing phosphomannan and further sulfonating it.SELECTED DRAWING: None 【課題】肝癌の再発、悪化および転移の抑制に用いる医薬組成物の提供。【解決手段】肝癌の再発、悪化および転移の抑制に用いる医薬組成物であって、治療有効量の特定の硫酸化オリゴ糖を含む医薬組成物。該硫酸化オリゴ糖は、１→３および/または１→２グルコシド結合によってマンノース単位２〜５個を結合したオリゴ糖分子で、リン酸基および硫酸基を有し、例えば、リン酸化マンナンを加水分解し、さらに、スルホン化することにより得られる。【選択図】なし