NOVEL COMPOUND, AND CARDIOMYOCYTE PROLIFERATION INDUCER CONTAINING THE SAME AS ACTIVE INGREDIENT, AND THERAPEUTIC AGENT FOR DISEASE ASSOCIATED WITH MYOCARDIAL DYSFUNCTION

NOVEL COMPOUND, AND CARDIOMYOCYTE PROLIFERATION INDUCER CONTAINING THE SAME AS ACTIVE INGREDIENT, AND THERAPEUTIC AGENT FOR DISEASE ASSOCIATED WITH MYOCARDIAL DYSFUNCTION

PROBLEM TO BE SOLVED: To provide a novel compound that amplifies the division and proliferation of conventional cardiomyocytes, and a cardiomyocyte proliferation inducer containing the compound, and a therapeutic agent for disease associated with myocardial dysfunction containing the compound.SOLUTI...

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Bibliographische Detailangaben
Hauptverfasser: TAKEDA NORIFUMI, HATA YUTAKA, KOMURO KAZUNARI, SAITO TATSUO, UCHIYAMA NAONOBU, HARA HIRONORI
Format: Patent
Sprache:eng ; jpn
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a novel compound that amplifies the division and proliferation of conventional cardiomyocytes, and a cardiomyocyte proliferation inducer containing the compound, and a therapeutic agent for disease associated with myocardial dysfunction containing the compound.SOLUTION: The present invention provides a compound represented by the following formula (1) [where Ris an allyl group and the like, Ris a fluorothienyl group and the like] or a salt or solvate thereof.SELECTED DRAWING: None 【課題】既存心筋細胞の分裂・増殖を増幅させる新規化合物、並びに該化合物を含む心筋細胞増殖誘導剤及び心筋の機能障害を伴う疾患の治療剤を提供することを目的とする。【解決手段】下記式（1）［式中、R1は、アリル基等であり、R2は、フルオロチエニル基等である］により表される化合物又はその塩もしくは溶媒和物。【選択図】なし