ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING ANTIMICROBIAL COMPOUNDS

PROBLEM TO BE SOLVED: To provide antimicrobial agents, in particular, antimicrobial agents having activity against resistant pathogenic bacterial organisms.SOLUTION: The invention provides imidazopyrimidine compounds represented by formula (IIa) in the figure. (D and E are single bonds; F is H; A is Calkyl, O, NR, a 3-14 membered saturated/unsaturated/aromatic heterocycle/carbocycle, or the like; G is Calkyl, O, C(=O), a 3-14 membered saturated/unsaturated/aromatic heterocycle/carbocycle, or the like; B and H are each a 3-14 membered saturated/unsaturated/aromatic heterocycle/carbocycle; C and J are each H, halogen, CF-CN, NO, OH, or a 3-14 membered saturated/unsaturated/aromatic heterocycle/carbocycle.)SELECTED DRAWING: None 【課題】新規な抗微生物剤、特に耐性のある病原性細菌性生物に対する活性を有する抗微生物剤の提供。【解決手段】式（ＩＩａ）で表されるイミダゾピリミリジン化合物。（Ｄ及びＥは単結合；ＦはＨ；ＡはＣ１〜８のアルキル、Ｏ、ＮＲ６、３〜１４員の飽和／不飽和／芳香族の複素環／炭素環等；ＧはＣ１〜８のアルキル、Ｏ、Ｃ（＝Ｏ）、３〜１４員の飽和／不飽和／芳香族の複素環／炭素環等；Ｂ及びＨは、３〜１４員の飽和／不飽和／芳香族の複素環／炭素環；Ｃ及びＪはＨ、ハロゲン、ＣＦ３−ＣＮ、ＮＯ２、ＯＨ、３〜１４員の飽和／不飽和／芳香族の複素環／炭素環）【選択図】なし