COPOLYMER, COATING AGENT USING THE SAME AND COATING METHOD

PROBLEM TO BE SOLVED: To provide a copolymer for coating a physiologically active substance on various substrates.SOLUTION: There is provided a copolymer having a copolymerization ratio of 2-methacryloyloxyethyl phosphorylcholine, butyl methacrylate and 2-methacryloyloxyethyl succinate of 15-50:40-7...

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Hauptverfasser:	YAMADA SATOSHI, SHIBA KIYOTAKA, NODA TOMOZUMI, SAKAMOTO NOBUYUKI, HIBINO KAZUHIRO
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	ADHESIVES CHEMICAL PAINT OR INK REMOVERS CHEMISTRY COATING COMPOSITIONS, e.g. PAINTS, VARNISHES ORLACQUERS COMPOSITIONS BASED THEREON CORRECTING FLUIDS DYES FILLING PASTES INKS INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS MEASURING METALLURGY MISCELLANEOUS APPLICATIONS OF MATERIALS MISCELLANEOUS COMPOSITIONS NATURAL RESINS ORGANIC MACROMOLECULAR COMPOUNDS PAINTS PASTES OR SOLIDS FOR COLOURING OR PRINTING PHYSICS POLISHES TESTING THEIR PREPARATION OR CHEMICAL WORKING-UP USE OF MATERIALS THEREFOR WOODSTAINS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a copolymer for coating a physiologically active substance on various substrates.SOLUTION: There is provided a copolymer having a copolymerization ratio of 2-methacryloyloxyethyl phosphorylcholine, butyl methacrylate and 2-methacryloyloxyethyl succinate of 15-50:40-75:2-20 and a molecular weight of 300,000. There is provided a coating agent which activates a carboxyl group in the copolymer to bind a physiologically active substance. There are provided: a coating agent in which the physiologically active substance includes a nucleic acid, a polypeptide, biotin, avidin, streptavidin and an analog thereof; and a method for coating the copolymer bonded with the physiological active substrate on various substrates as a coating agent.SELECTED DRAWING: None 【課題】種々の基材に生理活性物質をコーティングするための共重合体を提供する。【解決手段】２−メタクリロイルオキシエチルホスホリルコリン、メタクリル酸ブチル、２−メタクリロイルオキシエチルコハク酸の共重合比が１５〜５０：４０〜７５：２〜２０であり、分子量３００，０００以上である共重合体。前記共重合体中のカルボキシル基を活性化して生理活性物質を結合するコーティング剤。前記生理活性物質が核酸、ポリペプチド、ビオチン、アビジン、スレプトアビジン及びこれらの類縁体を含むものであるコーティング剤、前記生理活性物質を結合した前記共重合体をコーティング剤として種々の基材にコートする方法。【選択図】なし