USE OF MAS G-PROTEIN-COUPLED RECEPTOR AGONISTS AND ANTAGONISTS, AS APOPTOTIC-ACTIVITY MODULATORS FOR STUDY, PREVENTION AND TREATMENT OF DISEASES

PROBLEM TO BE SOLVED: To provide pharmaceutical compositions for use in gene therapy of diseases and for treatment of organic alterations produced by aging.SOLUTION: Pharmaceutical compositions for use in gene therapy of diseases and for treatment of organic alterations produced by aging contains cD...

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Hauptverfasser: DE CASTRO LEAL MARCELO, SILVA LULA IVANA, SINISTERRA RUBEN DARIO, LENICE KAPPES BECKER, DE FRANCA LUIZ RENATO, DE OLIVEIRA SAMPAIO WALKYRIE NEYDE, BARROS DE SOUSA FREDERICO, FREZARD FREDERIC JEAN GEORGES, VELOSO BRANT PINHEIRO SERGIO, SOUZA DOS SANTOS ROBSON AUGUSTO, DOS REIS ADELINA MARTHA, CAMPAGNOLE-SANTOS MARIA JOSE, FERREIRA ANDERSON JOSE, DE FARIA E SILVA RAPHAEL
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Sprache:eng ; jpn
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide pharmaceutical compositions for use in gene therapy of diseases and for treatment of organic alterations produced by aging.SOLUTION: Pharmaceutical compositions for use in gene therapy of diseases and for treatment of organic alterations produced by aging contains cDNAs that encode peptide sequences corresponding to Angiotensin-(1-7) or its agonist A-779.SELECTED DRAWING: Figure 10 【課題】病気の遺伝子治療において使用するための、および老化により生じる器官の変化の治療のための医薬組成物の提供。【解決手段】アンギオテンシン−(1−7)又はそのアンタゴニストであるA−779に対応するペプチド配列をコードするcDNAを含んでなる、病気の遺伝子治療において使用するための、および老化により生じる器官の変化の治療のための医薬組成物。【選択図】図10