HAIR GROWTH INHIBITOR

PROBLEM TO BE SOLVED: To provide hair growth inhibitors which inhibit the growth of the hair by inhibiting the expression of keratin gene KRT85 and/or KRT36 and which are also useful in depilation or epilation.SOLUTION: Provided is a hair growth inhibitor containing a compound represented by formula (1) as an active ingredient.The compound is obtained from the dry bark extract of Euonymus atropurpureus which is a Celastraceae plant or the dry root extract of Asclepias syriaca which is an Asclepiadoideae plant.[Ris a methyl group, a hydroxymethyl group, an aldehyde group or a carboxy group; and Ris an H or a monosaccharide residue.]SELECTED DRAWING: None 【課題】ケラチン遺伝子ＫＲＴ８５及び／又はＫＲＴ３６の発現を抑制することにより、毛の成長を抑制し、除毛又は脱毛にも有用な毛成長抑制剤の提供。【解決手段】式（１）で表される化合物を有効成分とする毛成長抑制剤。該化合物は、ニシキギ科植物であるイースタンワーフーの乾燥樹皮抽出物又はガガイモ科植物であるオオトウワタの乾燥根抽出物から得る前記化合物。［Ｒ１はメチル基、ヒドロキシメチル基、アルデヒド基又はカルボキシ基；Ｒ２はＨ又は単糖残基］【選択図】なし