CARRIER FOR AFFINITY CHROMATOGRAPHY, CHROMATOGRAPHY COLUMN, PURIFICATION METHOD, AND TARGET MATERIAL PURIFIED BY THE METHOD

CARRIER FOR AFFINITY CHROMATOGRAPHY, CHROMATOGRAPHY COLUMN, PURIFICATION METHOD, AND TARGET MATERIAL PURIFIED BY THE METHOD

PROBLEM TO BE SOLVED: To provide a carrier for affinity chromatography having a high flow rate characteristic and target material capture characteristic although a protein ligand is used.SOLUTION: A carrier for affinity chromatography is modified by a hydrophilic polymer and linker compound. In this...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: SHIOTANI TOMONORI, NAKAMURA SATOSHI
Format: Patent
Sprache:eng ; jpn
Schlagworte:
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:PROBLEM TO BE SOLVED: To provide a carrier for affinity chromatography having a high flow rate characteristic and target material capture characteristic although a protein ligand is used.SOLUTION: A carrier for affinity chromatography is modified by a hydrophilic polymer and linker compound. In this carrier, a protein ligand is further fixed through an active group on the linker compound fixed on a support body, and the linker length between the ligand and the support body is 30 or more in atomic number.SELECTED DRAWING: None 【課題】タンパク質のリガンドが使用されているにも拘らず、流速特性と標的物質捕捉特性に優れたアフィニティークロマトグラフィー用担体を提供すること。【解決手段】親水性高分子及びリンカー化合物により改質されたアフィニティークロマトグラフィー用担体であって、支持体に固定されたリンカー化合物上の活性基を通してタンパク質のリガンドがさらに固定され、且つ、前記リガンドと前記支持体との間のリンカー長が、原子数で３０以上であることを特徴とする、アフィニティークロマトグラフィー用担体。【選択図】なし