COMPOSITE GRANULE COMPRISING SUGAR OR SUGAR ALCOHOL, SWELLABLE BINDER, DISINTEGRATOR AND SUPERABSORBENT EXCIPIENT AND METHOD FOR PRODUCING THE SAME

PROBLEM TO BE SOLVED: To provide a composite granule that is optimal for a tablet, preferably an intraoral disintegrable tablet (OD tablet) to excel at disintegration and have proper hardness.SOLUTION: The present invention provides a composite granule comprising sugar or sugar alcohol, swellable bi...

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Hauptverfasser: UEMURA TOSHINOBU, URAMATSU SHUNJI, SHIMAMOTO TOSHIO, MORISANE SHINICHI
Format: Patent
Sprache:eng ; jpn
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a composite granule that is optimal for a tablet, preferably an intraoral disintegrable tablet (OD tablet) to excel at disintegration and have proper hardness.SOLUTION: The present invention provides a composite granule comprising sugar or sugar alcohol, swellable binder, disintegrator and superabsorbent excipient.SELECTED DRAWING: None 【課題】 本発明は、錠剤、好ましくは口腔内崩壊錠(OD錠)が崩壊性に優れ、適正な硬度を有するのに最適な複合化造粒物を提供する。【解決手段】 糖又は糖アルコール、膨潤型結合剤、崩壊剤及び高吸収性賦形剤を含む複合化造粒物。【選択図】なし