LONG-LASTING PHARMACEUTICAL FORMULATION

PROBLEM TO BE SOLVED: To provide a safe and effective long-lasting pharmaceutical formulation.SOLUTION: The present invention provides a long-lasting therapeutic formulation and a method for the use thereof. The formulation comprises a genetically modified micro-organ that comprises a vector compris...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
1. Verfasser: PEARLMAN ANDREW L
Format: Patent
Sprache:eng ; jpn
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:PROBLEM TO BE SOLVED: To provide a safe and effective long-lasting pharmaceutical formulation.SOLUTION: The present invention provides a long-lasting therapeutic formulation and a method for the use thereof. The formulation comprises a genetically modified micro-organ that comprises a vector comprising a nucleic acid sequence operably linked to one or more regulatory sequences. Here, the nucleic acid sequence encodes a therapeutic polypeptide, such as erythropoietin or interferon-α.SELECTED DRAWING: Figure 1 【課題】安全で効果的な長期持続性の医薬製剤を提供する。【解決手段】本発明は、長期持続性の治療用製剤とそれらの使用の方法へ向けられ、ここで該製剤は、1以上の調節配列へ機能可能的に連結した核酸配列を含むベクターを含む遺伝子修飾された微小器官を含み、ここで核酸配列は、エリスロポエチン又はインターフェロンαのような治療用ポリペプチドをコードする。【選択図】図1