LIPOSOME FORMULATION OF POLYPHENOL AND PRODUCTION METHOD THEREOF

PROBLEM TO BE SOLVED: To provide liposome formulations that stabilize polyphenol and to provide production methods thereof.SOLUTION: A formulation is made as liposomes, with acidic phospholipid, from an acidic solution containing: a compound represented by the following structural formula, and salts...

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Hauptverfasser: SAI MASAHIKO, YANAE KOJI, SANO SHOKO
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creator SAI MASAHIKO
YANAE KOJI
SANO SHOKO
description PROBLEM TO BE SOLVED: To provide liposome formulations that stabilize polyphenol and to provide production methods thereof.SOLUTION: A formulation is made as liposomes, with acidic phospholipid, from an acidic solution containing: a compound represented by the following structural formula, and salts and glycosides thereof; scirpusin A, scirpusin B, scirpusin C, Rhapontigenin, isorhapontigenin, and astringin; as well as polyphenol selected from catechin, anthocyanidin, and salts and glycosides thereof. [R-Rare each independently -H, -OH, or -OR. (R is an alkyl group of C1-C12.)]SELECTED DRAWING: None 【課題】ポリフェノールを安定化するリポソーム製剤およびその製造方法の提供。【解決手段】下記構造式で表される化合物、及びその塩及び配糖体;スキルプシンA、スキルプシンB、スキルプシンC、ラポンチゲニン、イソラポンチゲニン、及びアストリンジン;並びにカテキン、アントシアニジン、及びその塩及び配糖体から選択されるポリフェノールを含有した酸性溶液を酸性リン脂質でリポソームとした製剤。[R1〜R6は、各々独立に、−H、−OH又は−OR(RはC1〜C12のアルキル基)]【選択図】なし
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
title LIPOSOME FORMULATION OF POLYPHENOL AND PRODUCTION METHOD THEREOF
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