4-ALKOXY-5-(TRIFLUOROMETHYL)PYRIMIDINE DERIVATIVE AND METHOD FOR PRODUCING THE SAME

PROBLEM TO BE SOLVED: To provide a 5-(trifluoromethyl)pyrimidine derivative which is useful as a pharmaceutical and agrochemical intermediate and an electronic material intermediate and to provide a method for producing the same.SOLUTION: There is provided a method for obtaining a 5-(trifluoromethyl)pyrimidine derivative represented by the formula (1) and a derivative represented by the formula (1) by oxidizing a 4-phenylthio-5-(trifluoromethyl)pyrimidine derivative to produce a sulfoxide, followed by reacting with a metal alkoxide. [Rand Rrepresent H, a methyl group, an alkyl group or the like; and Rrepresents an alkyl group, a benzyl group or the like.]SELECTED DRAWING: None 【課題】医農薬中間体及び電子材料中間体として有用な５−（トリフルオロメチル）ピリミジン誘導体およびその製造方法の提供。【解決手段】式（１）で表される５−（トリフルオロメチル）ピリミジン誘導体及び４−フェニルチオ−５−（トリフルオロメチル）ピリミジン誘導体を酸化しスルホキシドとした後、金属アルコキシドと反応させ、式（１）で表される誘導体を得る製造方法。［Ｒ１及びＲ２はＨ、メチル基、アルキル基等；Ｒ３はアルキル基、ベンジル基等］【選択図】なし