THERAPEUTIC EFFECTS OF BRYOSTATIN, BRYOLOG, AND OTHER RELATED SUBSTANCES ON HEAD TRAUMA-INDUCED MEMORY IMPAIRMENT AND BRAIN INJURY

PROBLEM TO BE SOLVED: To provide a pharmaceutical composition effective in the treatment of head injury.SOLUTION: The invention provides a pharmaceutical composition containing a protein-kinase C (PKC) activator, such as a bryostatin, 4-methylcatechol acetic acid (MCBA), or a derivative of other met...

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Bibliographische Detailangaben
Hauptverfasser:	ZOHAR OPHIR, ALKON DANIEL L
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a pharmaceutical composition effective in the treatment of head injury.SOLUTION: The invention provides a pharmaceutical composition containing a protein-kinase C (PKC) activator, such as a bryostatin, 4-methylcatechol acetic acid (MCBA), or a derivative of other methylcatechol, and a pharmaceutically acceptable carrier.SELECTED DRAWING: Figure 3 【課題】頭部外傷の治療に有効な医薬組成物の提供。【解決手段】ブリオスタチン等のプロテインキナーゼC（PKC）アクチベータ、4-メチルカテコール酢酸（MCBA）、又は他のメチルカテコールの誘導体、及び薬学的に許容される担体を含む医薬組成物。【選択図】図３