MANUFACTURING METHOD OF HYDROXYLATED FATTY ACID COMPOUND

PROBLEM TO BE SOLVED: To provide a manufacturing method of a hydroxylated fatty acid compound which is used for an anti-wrinkle agent using the microalga, the intestine protective agent, the hyperglycemia inhibitor, intermediates of various compounds, and the like.SOLUTION: A manufacturing method of a hydroxylated fatty acid compound is provided by incubating microalga belonging to genus Chlorosarcinopsis, and collecting the generated hydroxylated fatty acid compound. The manufacturing method of the hydroxylated fatty acid compound is provided in which the microalga contains 18S rDNA with a specific base sequence, or contains 18S rDNA having 90% or more homologous with a specific base sequence in which a base corresponding to position 349 of the specific base sequence is adenine. The manufacturing method of the hydroxylated fatty acid compound is provided in which the hydroxylated fatty acid compound is 10-hydroxyoctadecanoic acid.SELECTED DRAWING: None 【課題】微細藻類を用いた抗しわ剤、腸管保護剤、血糖値上昇抑制剤、及び各種化合物の中間体等に利用される水酸化脂肪酸化合物の製造方法の提供。【解決手段】クロロサルシノプシス属に属する微細藻類を培養し、生成された水酸化脂肪酸化合物を回収し、水酸化脂肪酸化合物の製造方法であって、前記微細藻類が、特定の塩基配列の18S rDNA、又は、特定の塩基配列に対して90％以上の相同性を有し、かつ特定の塩基配列の349位に相当する塩基がアデニンである18S rDNA、を有する、水酸化脂肪酸化合物の製造方法。前記水酸化脂肪酸化合物が１０−ヒドロキシオクタデカン酸である製造方法。【選択図】なし