4-PHENYLTHIO-5-(TRIFLUOROMETHYL) PYRIMIDINE DERIVATIVE AND METHOD FOR PRODUCING THE SAME
PROBLEM TO BE SOLVED: To provide a 4-phenylthio-5-(trifluoromethyl) pyrimidine derivative that is useful as a medical/agrochemical intermediate and an electronic material intermediate and is substituted by an aniline derivative at the 2-position, and a method for producing the same.SOLUTION: The pre...
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| Format: | Patent |
| Sprache: | eng ; jpn |
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| Zusammenfassung: | PROBLEM TO BE SOLVED: To provide a 4-phenylthio-5-(trifluoromethyl) pyrimidine derivative that is useful as a medical/agrochemical intermediate and an electronic material intermediate and is substituted by an aniline derivative at the 2-position, and a method for producing the same.SOLUTION: The present invention provides a method for producing a 4-phenylthio-5-(trifluoromethyl) pyrimidine derivative represented by formula (1), by the reaction between 2-chloro-4-phenylthio-5-(trifluoromethyl) pyrimidine and an aniline derivative in the presence of a base.SELECTED DRAWING: None
【課題】医農薬中間体及び電子材料中間体として有用な２位がアニリン誘導体で置換された４−フェニルチオ−５−（トリフルオロメチル）ピリミジン誘導体及びその製造方法の提供。【解決手段】式（１）で表される４−フェニルチオ−５−（トリフルオロメチル）ピリミジン誘導体を、塩基存在下、２−クロロ−４−フェニルチオ−５−（トリフルオロメチル）ピリミジンとアニリン誘導体との反応により製造する方法。【選択図】なし |
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