ANTHOZOA-DERIVED CHROMOPHORES/FLUOROPHORES AND METHODS FOR USING THE SAME

PROBLEM TO BE SOLVED: To provide Anthozoa-derived chromo/fluorescence proteins and mutants thereof as well as nucleic acid compositions encoding the same.SOLUTION: Specific proteins of interest include chromo/fluorescence proteins from the following specific anthozoa species: Anemonia majano, Clavul...

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Hauptverfasser: FRADKOV ARCADY FEDOROVICH, MATZ MIKHAIL VLADIMIROVICH, TERSKIKH ALEXEY, LUKYANOV SERGEY ANATOLIEVICH, LABAS YULII ALEKSANDROVICH
Format: Patent
Sprache:eng ; jpn
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide Anthozoa-derived chromo/fluorescence proteins and mutants thereof as well as nucleic acid compositions encoding the same.SOLUTION: Specific proteins of interest include chromo/fluorescence proteins from the following specific anthozoa species: Anemonia majano, Clavularia sp., Zoanthus sp., Discosoma striata, Discosoma sp. "red", Anemonia sulcata, Discosoma sp. "green", Discosoma sp. "magenta" and mutants thereof. Also provided are fragments of the subject proteins and nucleic acids encoding the same, as well as antibodies to the subject proteins, transgenic cells and organisms. Also kits for use in applications that include the subject proteins are provided. 【課題】花虫類に由来する色素/蛍光タンパク質およびそれらの変異体と同様に、それらをコードする核酸組成物を提供する。【解決手段】対象の特異的なタンパク質は、以下の特定の花虫類種に由来する色素/蛍光タンパク質を含む:アネモニア・マジャノ(Anemonia majano)、ハナヅタ(Clavularia)種、ゾアンサス(Zoanthus)種、ディスコソマ・ストリアタ(Discosoma striata)、ディスコソマ(Discosoma)種「赤色」、アネモニア・スルカタ(Anemonia sulcata)、ディスコソマ(Discosoma)種「緑色」、ディスコソマ(Discosoma)種「深紅色」、およびそれらの変異体。対象タンパク質の断片と、それらをコードする核酸と同様に、対象タンパク質に対する抗体、およびトランスジェニック細胞および生物。対象タンパク質を含むような応用に使用されるキット。【選択図】図6