METHOD AND KIT FOR PREDICTING CANCER PROGNOSIS, SCREENING METHOD OF DRUG FOR CANCER TREATMENT, CANCER CELL GROWTH INHIBITOR, DRUG FOR CANCER TREATMENT, AND METHOD AND KIT FOR PREDICTING DRUG EFFICACY OF mTOR INHIBITOR

PROBLEM TO BE SOLVED: To provide a method and kit for predicting cancer prognosis which can conveniently predict various cancer prognosis with high accuracy, a cancer cell growth inhibitor which has an excellent cancer cell growth inhibition ability, a drug for cancer treatment containing the cancer...

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Bibliographische Detailangaben
Hauptverfasser:	MIYAZONO KOHEI, KAWASAKI NATSUMI, KOINUMA DAIZO, ISOGAYA KAZUNOBU
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide a method and kit for predicting cancer prognosis which can conveniently predict various cancer prognosis with high accuracy, a cancer cell growth inhibitor which has an excellent cancer cell growth inhibition ability, a drug for cancer treatment containing the cancer cell growth inhibitor, a screening method for the drug for cancer treatment, and a method and kit for predicting the drug efficacy of an mTOR inhibitor which can conveniently predict the drug efficacy of the mTOR inhibitor with high accuracy.SOLUTION: Disclosed are a method for predicting cancer prognosis comprising a step of measuring at least any one of expression level and activity of TUFT1 in a sample derived from a patient, and a step of evaluating cancer prognosis using at least any one of the expression level and activity of TUFT1 as an indicator; and a method for predicting the drug efficacy of the mTOR inhibitor, and the like. 【課題】様々な癌の予後を確実性が高く、簡便に予測することができる癌の予後を予測するための方法及びキット、優れた癌細胞の増殖抑制能を有する癌細胞増殖抑制剤、前記癌細胞増殖抑制剤を含む癌治療薬、癌治療薬のスクリーニング方法、並びに、ｍＴＯＲ阻害剤の薬効を確実性が高く、簡便に予測することができるｍＴＯＲ阻害剤の薬効を予測するための方法及びキットを提供すること。【解決手段】患者由来の試料中におけるＴＵＦＴ１の発現量及び活性の少なくともいずれかを測定する工程と、前記ＴＵＦＴ１の発現量及び活性の少なくともいずれかを指標として、癌の予後を評価する工程とを含む、癌の予後を予測するための方法、ｍＴＯＲ阻害剤の薬効を予測するための方法などである。【選択図】なし