DEUTERATED CATECHOLAMINE DERIVATIVES AND MEDICAMENTS COMPRISING SAID COMPOUNDS

PROBLEM TO BE SOLVED: To provide deuterated catecholamine derivatives, which have improved pharmacokinetic and/or pharmacodynamic properties compared to compounds already known and which can be used for producing pharmaceuticals for prophylaxis of psychoses, particularly schizophrenia.SOLUTION: Ther...

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1. Verfasser:	ALKEN RUDOLF-GIESBERT
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	PROBLEM TO BE SOLVED: To provide deuterated catecholamine derivatives, which have improved pharmacokinetic and/or pharmacodynamic properties compared to compounds already known and which can be used for producing pharmaceuticals for prophylaxis of psychoses, particularly schizophrenia.SOLUTION: There are provided deuterated catecholamine derivatives such as L-2-amino-3,3-dideutero-3-(3,4-dihydroxyphenyl) propionic acid. 【課題】すでに知られている化合物に比較して改良された薬物動態学的および／または薬力学的特性を有する、精神病、特に統合失調症を予防するための医薬品を製造するために使用できる重水素化カテコールアミン誘導体を提供する。【解決手段】Ｌ−２−アミノ−３，３−ジデューテロ−３−（３，４−ジヒドロキシフェニル）プロピオン酸等の重水素化カテコールアミン誘導体。【選択図】なし