NOVEL USE OF N-SUBSTITUTED SULFONYL INDOLE DERIVATIVE COMPOUND

PROBLEM TO BE SOLVED: To provide a pharmaceutical composition that comprises an N-substituted sulfonyl indole derivative compound having proliferation inhibitory action for a wide range of cancer cells as an active ingredient.SOLUTION: An anticancer agent pharmaceutical composition comprises an N-su...

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Hauptverfasser: SUZUKI YUTARO, KAMIMURA DAISUKE, WATABE TAEKO, KAWAZOE YOSHINORI, ABE TAKAHIRO, YAMADA KAORU
Format: Patent
Sprache:eng ; jpn
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Zusammenfassung:PROBLEM TO BE SOLVED: To provide a pharmaceutical composition that comprises an N-substituted sulfonyl indole derivative compound having proliferation inhibitory action for a wide range of cancer cells as an active ingredient.SOLUTION: An anticancer agent pharmaceutical composition comprises an N-substituted sulfonyl indole derivative compound represented by the formula (1), having B12 melanoma cell proliferation inhibitory activity, where R is a lower alkyl group, an aryl group which may be substituted, or a heteroaryl group which may be substituted. 【課題】広範な癌細胞に対する増殖抑制作用を有するN−置換スルフォニルインドール誘導体化合物を有効成分として含有する医薬組成物の提供。【解決手段】式(1)で表されるB12メラノーマ細胞増殖阻害活性を有するN−置換スルフォニルインドール誘導体化合物を含有する抗癌剤医薬組成物。[Rは低級アルキル基、置換していてもよいアリール基、又は置換していてもよいヘテロアリール基]【選択図】なし