PERMEANT DELIVERY SYSTEM AND METHODS FOR USE THEREOF

PROBLEM TO BE SOLVED: To provide a system for the delivery of a permeant through a biological membrane of a subject.SOLUTION: This invention relates to a patch comprising at least one hydrophilic permeant, allowing at least part of the hydrophilic permeant to be dissolved in moisture received from a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GAURAV TOLIA, FRANK TAGLIAFERRI, CHANG SHULUN, YOGI PATEL, STUART MCRAE, JONATHAN EPPSTEIN, SMITH ALAN, DAVID ENSCORE
Format: Patent
Sprache:eng ; jpn
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Beschreibung
Zusammenfassung:PROBLEM TO BE SOLVED: To provide a system for the delivery of a permeant through a biological membrane of a subject.SOLUTION: This invention relates to a patch comprising at least one hydrophilic permeant, allowing at least part of the hydrophilic permeant to be dissolved in moisture received from a patient, positioning it in fluid communication with at least one formed pathway through a skin layer to draw subcutaneous fluid from the subject, and transdermally delivering it at a desired flux through the at least one formed pathway. 【課題】患者の生体膜を通って透過物をデリバリーするためのシステムの提供。【解決手段】少なくとも1つの親水性透過物を含むパッチであって、該親水性透過物の少なくとも一部が患者から受ける生体湿分に溶解することができ、皮膚層を通る少なくとも1つの形成された経路との流体通路に置くことにより、患者からの皮下液を引き出し、少なくとも1つの形成された経路を通って、所望の流動で浸透物を経皮的にデリバリーするパッチ。【選択図】なし