NOVEL SUBSTITUTED IMIDAZOQUINOLINE

PROBLEM TO BE SOLVED: To provide an imidazoquinoline derivative, and a pharmaceutical composition including an imidazoquinoline derivative.SOLUTION: Disclosed is an imidazoquinoline of formula I, including a substituted amine or an amide functional group in a 1-position and effective as a Toll-like...

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Hauptverfasser: THOMAS MAIER, HANS-PETER HOFMANN, KULKARNI SANJEEV A, JAGTAP ANIL P, ASTRID ZIMMERMANN, CHAURE GANESH S, GEKELER VOLKER
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creator THOMAS MAIER
HANS-PETER HOFMANN
KULKARNI SANJEEV A
JAGTAP ANIL P
ASTRID ZIMMERMANN
CHAURE GANESH S
GEKELER VOLKER
description PROBLEM TO BE SOLVED: To provide an imidazoquinoline derivative, and a pharmaceutical composition including an imidazoquinoline derivative.SOLUTION: Disclosed is an imidazoquinoline of formula I, including a substituted amine or an amide functional group in a 1-position and effective as a Toll-like receptor 7 activator. The compound is useful as an anticancer agent. 【課題】イミダゾキノリン誘導体、及び、イミダゾキノリン誘導体を含む医薬組成物を提供すること。【解決手段】置換アミン又はアミド官能基を1−位に含みかつトール様レセプター7アクティベータとして有効である式Iのイミダゾキノリンを開示する。これらの化合物は抗癌剤として有用である。【選択図】なし
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title NOVEL SUBSTITUTED IMIDAZOQUINOLINE
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