NOVEL SUBSTITUTED IMIDAZOQUINOLINE

PROBLEM TO BE SOLVED: To provide an imidazoquinoline derivative, and a pharmaceutical composition including an imidazoquinoline derivative.SOLUTION: Disclosed is an imidazoquinoline of formula I, including a substituted amine or an amide functional group in a 1-position and effective as a Toll-like...

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Bibliographische Detailangaben
Hauptverfasser:	THOMAS MAIER, HANS-PETER HOFMANN, KULKARNI SANJEEV A, JAGTAP ANIL P, ASTRID ZIMMERMANN, CHAURE GANESH S, GEKELER VOLKER
Format:	Patent
Sprache:	eng ; jpn
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	PROBLEM TO BE SOLVED: To provide an imidazoquinoline derivative, and a pharmaceutical composition including an imidazoquinoline derivative.SOLUTION: Disclosed is an imidazoquinoline of formula I, including a substituted amine or an amide functional group in a 1-position and effective as a Toll-like receptor 7 activator. The compound is useful as an anticancer agent. 【課題】イミダゾキノリン誘導体、及び、イミダゾキノリン誘導体を含む医薬組成物を提供すること。【解決手段】置換アミン又はアミド官能基を１−位に含みかつトール様レセプター７アクティベータとして有効である式Ｉのイミダゾキノリンを開示する。これらの化合物は抗癌剤として有用である。【選択図】なし